According to the results for the period from January to October 2025, 18.5 million packs of finished pharmaceuticals were sold on the Russian retail market that had been opened in pharmacies and dispensed to consumers in their primary packaging. This dispensing format is most common for products supplied in sachet dosage forms containing powders or granules used to prepare solutions, although some products are sold as individual blisters, bottles, and other dosage forms. Over the year, their volume declined by 17% (in packs), while, according to the RNC Pharma® database “Audit of Retail Sales of Pharmaceuticals in Russia (total sell out),” the total monetary volume of sales of such products in the reviewed period amounted to 22.9 billion rubles (at retail prices, including VAT) and remained almost unchanged compared with January–October 2024.

The absolute leader in sales of pharmaceuticals dispensed from opened consumer packs in January–October 2025 was Nimesil by Menarini. With total retail sales of this brand amounting to 6.87 billion rubles, around 26.2% of this sum accounted for fractional dispensing. Most frequently, consumer packs of this product are opened in the dosage form of granules 100 mg No. 30; for this form, the share of unit sales exceeds 40% in monetary terms and reaches 26.5% in physical units. Notably, the cost of a single dose for the consumer is significantly higher: the retail price of one sachet in pharmacies is 87% higher than in the case of purchasing a full pack. It is noteworthy that four brands in the top ten represent sachet-based dosage forms; in addition to Nimesil, these include Phosphalugel by Sanofi, Theraflu by Heleon, and Anvimax by Sotex.

The second highest result in terms of monetary volume of fractional sales was recorded for Pulmicort by AstraZeneca, with approximately 18.7% of its volume dispensed fractionally, most often in blocks containing five single-use containers. The ratio is generally similar for both the 0.25 mg/ml and 0.5 mg/ml suspensions, with a slight predominance of the latter; the share in physical units reaches 12.3%.

Within the top ten brands leading in the monetary volume of fractional sales, the lowest shares in physical units were observed for Goldline (Izvarino) and Anvimax (Sotex), at 3.1% and 3.2% respectively. Microlax, which is sold as individual micro-enemas, is dispensed fractionally in only 4% of cases. However, outside the top group in monetary terms, there are examples where fractional dispensing plays a critical role—for instance, more than 34% of sales of Senade (Dr. Reddy’s) occur as individual blisters, and unit sachets of Regidron (Valenta) account for 27% of its sales.

Table. Top 10 trademarks of medicinal products by share of sales with opened consumer packaging in the Russian retail pharmaceutical market in January–October 2025, percent (value)